Worldwide audit of blood transfusion practice in critically ill patients.

ABSTRACT: BACKGROUND:The aim was to describe transfusion practice in critically ill patients at an international level and evaluate the effects of red blood cell (RBC) transfusion on outcomes in these patients. METHODS:This was a pre-planned sub-study of the Intensive Care Over Nations audit, which involved 730 ICUs in 84 countries and included all adult patients admitted between 8 May and 18 May 2012, except admissions for routine postoperative surveillance. RESULTS:ICU and hospital outcomes were recorded. Among the 10,069 patients included in the audit, data related to transfusion had been completed for 9553 (mean age 60?±?18 years, 60% male); 2511 (26.3%) of these had received a transfusion, with considerable variation among geographic regions. The mean lowest hemoglobin on the day of transfusion was 8.3?±?1.7 g/dL, but varied from 7.8?±?1.4 g/dL in the Middle East to 8.9?±?1.9 g/dL in Eastern Europe. Hospital mortality rates were higher in transfused than in non-transfused patients (30.0% vs. 19.6%, p?

SUBMITTER: Vincent JL 

PROVIDER: S-EPMC5909204 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature