Ontology highlight
ABSTRACT:
SUBMITTER: Fueyo R
PROVIDER: S-EPMC5909450 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Nucleic acids research 20180401 7
During neurogenesis, dynamic developmental cues, transcription factors and histone modifying enzymes regulate the gene expression programs by modulating the activity of neural-specific enhancers. How transient developmental signals coordinate transcription factor recruitment to enhancers and to which extent chromatin modifiers contribute to enhancer activity is starting to be uncovered. Here, we take advantage of neural stem cells as a model to unravel the mechanisms underlying neural enhancer a ...[more]