Deviations in energy sensing predict long-term weight change in overweight Native Americans.

ABSTRACT:

Background/objectives

Energy expenditure (EE), as reflective of body energy demand, has been proposed to be the key driver of food intake, possibly influencing weight change in humans. Variation in this energy-sensing link (overeating relative to weight-maintaining energy requirements) may lead to weight gain over time.

Subjects/methods

Sixty-one overweight otherwise healthy Native Americans (age: 34.0 ± 7.9 years, body fat: 39.7 ± 9.5%, 36 males) were admitted to our clinical research unit for measurements of body composition by dual-energy X-ray absorptiometry, and 24-h EE and respiratory quotient (RQ) in a whole-room indirect calorimeter during energy balance and weight stability. Following this, ad libitum food intake was assessed for three days using computerized vendin

SUBMITTER: Basolo A 

PROVIDER: S-EPMC5930127 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature