Serious Adverse Events Significantly Reduce Patient-Reported Outcomes at 2-Year Follow-up: Nonoperative, Multicenter, Prospective NIH Study of 105 Patients.

ABSTRACT:

Study design

This is an analysis of a prospective 2-year study on nonoperative patients enrolled in the Adult Symptomatic Lumbar Scoliosis (ASLS) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) trial.

Objective

The purpose was to evaluate the impact of serious adverse events (SAEs) on patient-reported outcomes (PROs) in nonoperative management of ASLS as measured by Scoliosis Research Society-22 (SRS-22), Oswestry Disability Index (ODI), and Short Form-12 (SF-12) at 2-year follow-up.

Summary of background data

Little is known about PROs in the nonoperative management of ASLS or the prevalence and impact of SAEs on PROs.

Methods

The ASLS trial dataset was analyzed to identify adult lumbar scoliosis patients electively choosing or ra

SUBMITTER: Pugely AJ 

PROVIDER: S-EPMC5930151 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature