Long-term Fine Particulate Matter Exposure and Nonaccidental and Cause-specific Mortality in a Large National Cohort of Chinese Men.

ABSTRACT:

Background

Cohort studies in North America and western Europe have reported increased risk of mortality associated with long-term exposure to fine particles (PM_2.5), but to date, no such studies have been reported in China, where higher levels of exposure are experienced.

Objectives

We estimated the association between long-term exposure to PM_2.5 with nonaccidental and cause-specific mortality in a cohort of Chinese men.

Methods

We conducted a prospective cohort study of 189,793 men 40 y old or older during 1990-91 from 45 areas in China. Annual average PM_2.5 levels for the years 1990, 1995, 2000, and 2005 were estimated for each cohort location using a combination of satellite-based estimates, chemical transport model simulations, and

SUBMITTER: Yin P 

PROVIDER: S-EPMC5947939 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature