"Dip-and-read" paper-based analytical devices using distance-based detection with color screening.

ABSTRACT: An improved paper-based analytical device (PAD) using color screening to enhance device performance is described. Current detection methods for PADs relying on the distance-based signalling motif can be slow due to the assay time being limited by capillary flow rates that wick fluid through the detection zone. For traditional distance-based detection motifs, analysis can take up to 45 min for a channel length of 5 cm. By using a color screening method, quantification with a distance-based PAD can be achieved in minutes through a "dip-and-read" approach. A colorimetric indicator line deposited onto a paper substrate using inkjet-printing undergoes a concentration-dependent colorimetric response for a given analyte. This color intensity-based response has been converted to a distance-based s

SUBMITTER: Yamada K 

PROVIDER: S-EPMC5975359 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature