Efficient metal-free photochemical borylation of aryl halides under batch and continuous-flow conditions.

ABSTRACT: A rapid, chemoselective and metal-free C-B bond-forming reaction of aryl iodides and bromides in aqueous solution at low temperatures was discovered. This reaction is amenable to batch and continuous-flow conditions and shows exceptional functional group tolerance and broad substrate scope regarding both the aryl halide and the borylating reagent. Initial mechanistic experiments indicated a photolytically generated aryl radical as the key intermediate.

SUBMITTER: Chen K 

PROVIDER: S-EPMC6008923 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature