Nigella damascena L. Essential Oil-A Valuable Source of β-Elemene for Antimicrobial Testing.

ABSTRACT: The most commonly used plant source of β-elemene is Curcuma wenyujin Y. H. Chen & C. Ling (syn. of Curcuma aromatic Salisb.) with its content in supercritical CO₂ extract up to 27.83%. However, the other rich source of this compound is Nigella damascena L. essential oil, in which β-elemene accounts for 47%. In this work, the effective protocol for preparative isolation of β-elemene from a new source-N. damascena essential oil-using high performance counter-current chromatography HPCCC was elaborated. Furthermore, since sesquiterpens are known as potent antimicrobials, the need for finding new agents designed to combat multi-drug resistant strains was addressed and the purified target compound and the essential oil were tested for its activity against a panel of Gram-positive and Gram-negat

SUBMITTER: Sieniawska E 

PROVIDER: S-EPMC6017462 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature