Nut consumption and the risk of oesophageal squamous cell carcinoma in the Golestan Cohort Study.

ABSTRACT:

Background

Nut consumption has been inversely associated with gastric cancer incidence in US-based studies, but not with oesophageal cancer. However, there is aetiologic heterogeneity, among oesophageal squamous cell carcinoma (ESCC) cases in low-risk vs. high-risk populations. The objective of this study was to evaluate the association between nut consumption and risk of ESCC in a high-risk population.

Methods

The Golestan Cohort Study enroled 50,045 participants in Northeastern Iran, between 2004 and 2008. Intake of peanuts, walnuts and mixed nuts (including seeds) were assessed using a validated food frequency questionnaire at baseline. Cox proportional hazard models were used to estimate hazard ratios (HR) and 95% confidence intervals for subsequent ESCC adjusted for pot

SUBMITTER: Hashemian M 

PROVIDER: S-EPMC6048068 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature