Cone photoreceptor macular function and recovery after photostress in early non-exudative age-related macular degeneration.

ABSTRACT:

Purpose

To identify parameters from cone function and recovery after photostress that detect functional deficits in early non-exudative age-related macular degeneration (AMD) and to determine the repeatability of these parameters.

Methods

Cone-mediated visual function recovery after photostress was examined in three groups of subjects: young normal subjects (ages 20-29; N=8), older normal subjects (ages 50-90; N=9), and early non-exudative AMD subjects (ages 50-90; N=12). Eight AMD and four normal subjects were retested 1 year after the initial evaluation. Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity (VA) and parameters of cone function (baseline cone sensitivity and cone recovery half-life following photobleach) were measured and compared between AMD and

SUBMITTER: Rodriguez JD 

PROVIDER: S-EPMC6067527 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature