Patient-specific anatomical model for deep brain stimulation based on 7 Tesla MRI.

ABSTRACT:

Objective

Deep brain stimulation (DBS) requires accurate localization of the anatomical target structure, and the precise placement of the DBS electrode within it. Ultra-high field 7 Tesla (T) MR images can be utilized to create patient-specific anatomical 3D models of the subthalamic nuclei (STN) to enhance pre-surgical DBS targeting as well as post-surgical visualization of the DBS lead position and orientation. We validated the accuracy of the 7T imaging-based patient-specific model of the STN and measured the variability of the location and dimensions across movement disorder patients.

Methods

72 patients who underwent DBS surgery were scanned preoperatively on 7T MRI. Segmentations and 3D volume rendering of the STN were generated for all patients. For 21 STN-DBS cases,

SUBMITTER: Duchin Y 

PROVIDER: S-EPMC6104927 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature