Ontology highlight
ABSTRACT:
SUBMITTER: Qiao X
PROVIDER: S-EPMC6151504 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Qiao Xin X Sun Wei W Wang Chongzhi C Zhang Li L Li Ping P Wen Xiaodong X Yang Jie J Yuan Chunsu C
Molecules (Basel, Switzerland) 20170922 10
Colorectal cancer (CRC) is the third most common cancer in the world. <i>Oplopanax elatus</i> is widely used in traditional medicine. However, little is known about its pharmacological effects and bioactive compounds. We evaluated the effects of the polyyne-enriched extract from <i>O. elatus</i> (PEO) on the progression of colon carcinogenesis in <i>Apc</i><sup>Min/+</sup> mice. In addition, these effects were also investigated in HCT116 and SW480 cells. After PEO oral administration (0.2% diet) ...[more]