Global mRNA decay and 23S rRNA fragmentation in Gluconobacter oxydans 621H.

ABSTRACT:

Background

Gluconobacter oxydans is a strictly aerobic Gram-negative acetic acid bacterium used industrially for oxidative biotransformations due to its exceptional type of catabolism. It incompletely oxidizes a wide variety of carbohydrates regio- and stereoselectively in the periplasm using membrane-bound dehydrogenases with accumulation of the products in the medium. As a consequence, only a small fraction of the carbon and energy source enters the cell, resulting in a low biomass yield. Additionally, central carbon metabolism is characterized by the absence of a functional glycolysis and absence of a functional tricarboxylic acid (TCA) cycle. Due to these features, G. oxydans is a highly interesting model organism. Here we analyzed global mRNA decay in G. oxydans to describe it

SUBMITTER: Kranz A 

PROVIDER: S-EPMC6191907 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature