The challenges of muscle biopsy in a community based geriatric population.

ABSTRACT:

Objectives

To describe the difficulties of obtaining muscle samples using a Bergstrom needle technique in a frail older adult population. The data were obtained from a study primarily investigating immunosenescence in frailty. An intended research technique was skeletal muscle biopsy in a small subset of participants to investigate muscle morphology and local inflammatory factors.

Results

Forty healthy older adults and 37 frail older adults were considered for a Bergstrom needle muscle biopsy. Of these, 17.5% of healthy older adults and 94.6% of the frail older adults had single or multiple participant factors resulting in a contra-indication to muscle biopsy. 40.7% of healthy older female participants were at risk of a failed muscle biopsy due to low muscle mass. Considerin

SUBMITTER: Wilson D 

PROVIDER: S-EPMC6260758 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature