Chronic Cold Stress Alters the Skin Mucus Interactome in a Temperate Fish Model.

ABSTRACT: Temperate fish are particularly sensitive to low temperatures, especially in the northern Mediterranean area, where the cold season decreases fish-farm production and affects fish health. Recent studies have suggested that the skin mucus participates in overall fish defense and welfare, and therefore propose it as a target for non-invasive studies of fish status. Here, we determine the mucus interactome of differentially expressed proteins in a temperate fish model, gilthead sea bream (Sparus aurata), after chronic exposure to low temperatures (7 weeks at 14°C). The differentially expressed proteins were obtained by 2D-PAGE of mucus soluble proteins and further assessed by STRING analyses of the functional interactome based on protein-protein interactions. Complementarily, we determ

SUBMITTER: Sanahuja I 

PROVIDER: S-EPMC6336924 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature