Quilty Lesions in the Endomyocardial Biopsies after Heart Transplantation.

ABSTRACT:

Background

The aim of this study was to investigate the clinical significance of Quilty lesions in endomyocardial biopsies (EMBs) of cardiac transplantation patients.

Methods

A total of 1190EMBs from 117 cardiac transplantation patients were evaluated histologically for Quilty lesions,acute cellular rejection, and antibody-mediated rejection. Cardiac allograft vasculopathy wasdiagnosed by computed tomography coronary angiography. Clinical information, including thepatients' survival was retrieved by a review of medical records.

Results

Eighty-eight patients(75.2%) were diagnosed with Quilty lesions, which were significantly associated with acute cellularrejection, but not with acute cellular rejection ≥ 2R or antibody-mediated rejection. In patientsdiagnosed with both

SUBMITTER: Cho H 

PROVIDER: S-EPMC6344801 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature