Ontology highlight
ABSTRACT:
SUBMITTER: Rizzardi LF
PROVIDER: S-EPMC6348048 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Nature neuroscience 20190114 2
Epigenetic modifications confer stable transcriptional patterns in the brain, and both normal and abnormal brain function involve specialized brain regions. We examined DNA methylation by whole-genome bisulfite sequencing in neuronal and non-neuronal populations from four brain regions (anterior cingulate gyrus, hippocampus, prefrontal cortex, and nucleus accumbens) as well as chromatin accessibility in the latter two. We find pronounced differences in both CpG and non-CpG methylation (CG-DMRs a ...[more]