Anti-infective potential of hydroalcoholic extract of Punica  granatum peel against gram-negative bacterial pathogens.

ABSTRACT: Background:Punica granatum extracts have been prescribed in traditional medicine for management of a variety of disease conditions including microbial infections. Generation of scientific evidence for validation of P. granatum peel extract's anti-pathogenic efficacy is required. Methods: Hydroalcoholic extract of P. granatum peel (PGPE), prepared by microwave assisted extraction method was evaluated for its quorum-modulatory potential against two different human-pathogenic bacteria viz. Chromobacterium violaceum and Pseudomonas aeruginosa. Results: This extract was able to modulate in vitro production of quorum sensing-regulated pigments in both these test bacteria at ≥5 μg/ml. Virulence traits of P. aeruginosa like haem

SUBMITTER: Joshi C 

PROVIDER: S-EPMC6392158 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature