Differential exposure to organophosphate flame retardants in mother-child pairs.

ABSTRACT:

Background

Humans are ubiquitously exposed to flame retardants, including organophosphate esters (OPEs), through direct contact with consumer products or exposure through household dust. Children are at increased risk because of their proximity to dust, hand-to-mouth activity, and the importance of childhood as a critical period in neurodevelopment.

Objectives

To quantify differences in exposure levels between mothers and children (three to six years of age), we analyzed urinary metabolites of OPEs. We additionally assessed the ability of silicone wristbands (measuring ambient exposure) to predict urinary metabolite concentrations.

Methods

We selected 32 mother and child dyads from an existing cohort. Participants provided baseline urine samples and wore wristbands fo

SUBMITTER: Gibson EA 

PROVIDER: S-EPMC6460923 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature