Breast cancer mortality in synchronous bilateral breast cancer patients.

ABSTRACT:

Background

Evidence suggests that patients with synchronous bilateral breast cancer (SBBC), diagnosed within 4 months, have an inferior prognosis compared to unilateral breast cancer (UBC) patients. Using data from nationwide Danish clinical databases, this cohort study investigated whether the inferior prognosis could be explained by SBBC patients having a more aggressive disease, or whether the prognosis could be explained by the fact that they have two simultaneous cancers.

Methods

Patients were diagnosed from 1999-2015. The main outcome was excess mortality, subtracting background population mortality from observed mortality. Differences between SBBC and UBC patients were evaluated by rate ratios (RR) and estimated by Poisson regression.

Results

In total, 1214 SBB

SUBMITTER: Mejdahl MK 

PROVIDER: S-EPMC6461871 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature