Chronotherapy versus conventional statins therapy for the treatment of hyperlipidaemia.
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ABSTRACT:
SUBMITTER: Izquierdo-Palomares JM
PROVIDER: S-EPMC6464955 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Chronotherapy versus conventional statins therapy for the treatment of hyperlipidaemia.
Izquierdo-Palomares Jose Manuel JM Fernandez-Tabera Jesus Maria JM Plana Maria N MN Añino Alba Almudena A Gómez Álvarez Pablo P Fernandez-Esteban Inmaculada I Saiz Luis Carlos LC Martin-Carrillo Pilar P Pinar López Óscar Ó
The Cochrane database of systematic reviews 20161126
<h4>Background</h4>Elevated levels of total cholesterol and low-density lipoprotein play an important role in the development of atheromas and, therefore, in cardiovascular diseases. Cholesterol biosynthesis follows a circadian rhythm and is principally produced at night (between 12:00 am and 6:00 am). The adjustment of hypolipaemic therapy to biologic rhythms is known as chronotherapy. Chronotherapy is based on the idea that medication can have different effects depending on the hour at which i ...[more]
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