PD-1 Ligand Expression in Epithelial Thyroid Cancers: Potential Clinical Implications.
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ABSTRACT:
SUBMITTER: Ulisse S
PROVIDER: S-EPMC6471477 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
PD-1 Ligand Expression in Epithelial Thyroid Cancers: Potential Clinical Implications.
Ulisse Salvatore S Tuccilli Chiara C Sorrenti Salvatore S Antonelli Alessandro A Fallahi Poupak P D'Armiento Eleonora E Catania Antonio A Tartaglia Francesco F Amabile Maria Ida MI Giacomelli Laura L Metere Alessio A Cornacchini Nicola N Pironi Daniele D Carbotta Giovanni G Vergine Massimo M Monti Massimo M Baldini Enke E
International journal of molecular sciences 20190320 6
The new immunotherapy targeting the programmed cell death 1 (PD-1) receptor and its cognate ligand PD-L1 has renewed hopes of eradicating the most difficult human cancers to treat. Among these, there are the poorly differentiated and anaplastic thyroid cancers, unresponsive to all the therapies currently in use. In the present review we will summarize information regarding the expression of PD-L1 in the different thyroid cancer histotypes, its correlation with clinicopathological features, and i ...[more]
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