Nanostructured ZnO as Multifunctional Carrier for a Green Antibacterial Drug Delivery System-A Feasibility Study.

ABSTRACT: The physico⁻chemical and biological properties of nanostructured ZnO are combined with the non-toxic and eco-friendly features of the scCO₂-mediated drug loading technique to develop a multifunctional antimicrobial drug delivery system for potential applications in wound healing. Two nanostructured ZnO (NsZnO) with different morphologies were prepared through wet organic-solvent-free processes and characterized by means of powder X-ray diffraction, field emission scanning electron microscopy (FESEM), and nitrogen adsorption analysis. The antimicrobial activity of the two samples against different microbial strains was investigated together with the in vitro Zn2+ release. The results indicated that the two ZnO nanostructures exhibited the following activity: S. aureus > C. albicans > K. pne

SUBMITTER: Leone F 

PROVIDER: S-EPMC6473990 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature