Increased elasticity of melanoma cells after low-LET proton beam due to actin cytoskeleton rearrangements.
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ABSTRACT:
SUBMITTER: Jasinska-Konior K
PROVIDER: S-EPMC6504917 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Increased elasticity of melanoma cells after low-LET proton beam due to actin cytoskeleton rearrangements.
Jasińska-Konior Katarzyna K Wiecheć Olga O Sarna Michał M Panek Agnieszka A Swakoń Jan J Michalik Marta M Urbańska Krystyna K Elas Martyna M
Scientific reports 20190507 1
Cellular response to non-lethal radiation stress include perturbations in DNA repair, angiogenesis, migration, and adhesion, among others. Low-LET proton beam radiation has been shown to induce somewhat different biological response than photon radiation. For example, we have shown that non-lethal doses of proton beam radiation inhibited migration of cells and that this effect persisted long-term. Here, we have examined cellular elasticity and actin cytoskeleton organization in BLM cutaneous mel ...[more]
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