PTMphinder: an R package for PTM site localization and motif extraction from proteomic datasets.

ABSTRACT:

Background

Mass-spectrometry-based proteomics is a prominent field of study that allows for the unbiased quantification of thousands of proteins from a particular sample. A key advantage of these techniques is the ability to detect protein post-translational modifications (PTMs) and localize them to specific amino acid residues. These approaches have led to many significant findings in a wide range of biological disciplines, from developmental biology to cancer and infectious diseases. However, there is a current lack of tools available to connect raw PTM site information to biologically meaningful results in a high-throughput manner. Furthermore, many of the available tools require significant programming knowledge to implement.

Results

The R package PTMphinder was d

SUBMITTER: Wozniak JM 

PROVIDER: S-EPMC6555389 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature