Antibiotic prophylaxis in ragged placental membranes: a prospective, multicentre, randomized trial.

ABSTRACT:

Background

Ragged placental membranes is a distinct entity from retained placenta and not uncommonly reported in midwifery texts. Although the incidence of postpartum endometritis is merely 1-5% after vaginal births, it remains the most common source of puerperal sepsis, contributing up to 15% of maternal mortality in low income countries. Geographically-remote centres in Malaysia prophylactically administer antibiotics for women with ragged placental membranes after vaginal birth, extrapolating evidence from retained placenta. We sought to clarify the rationale in continuing such practices.

Methods

This was an open-label, prospective, multicentre, randomized trial. Three hospitals where the current protocol was to administer prophylactic amoxycillin-clavulanic acid served a

SUBMITTER: Voon HY 

PROVIDER: S-EPMC6624936 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature