Highlighted role of VEGFA in follow up of celiac disease.

ABSTRACT:

Aim

Evolution of gene expression change of intestine tissue in celiac patients to find a new molecular prospective of disease is the aim of this study.

Background

Celiac disease (CD) as an autoimmune disease is known as an immune reaction response to the gluten in patients. It is reported that genetic and environmental conditions are important in onset and progress of CD.

Methods

gene expression profiles of intestinal tissue in 12 celiac patients and 12 healthy controls from gene expression omnibus (GEO) were downloaded and verified by boxplot analysis. The significant and selected differentially expressed genes (DEGs) were included protein-protein interaction (PPI) network analysis. The central nodes were identified by network analyzer.

Results

The network was

SUBMITTER: Rezaei-Tavirani S 

PROVIDER: S-EPMC6668760 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature