Sustained influence of infections on prostate-specific antigen concentration: An analysis of changes over 10 years of follow-up.

ABSTRACT:

Background

To extend our previous observation of a short-term rise in prostate-specific antigen (PSA) concentration, a marker of prostate inflammation and cell damage, during and immediately following sexually transmitted and systemic infections, we examined the longer-term influence of these infections, both individually and cumulatively, on PSA over a mean of 10 years of follow-up in young active duty U.S. servicemen.

Methods

We measured PSA in serum specimens collected in 1995-7 (baseline) and 2004-6 (follow-up) from 265 men diagnosed with chlamydia (CT), 72 with gonorrhea (GC), 37 with non-chlamydial, non-gonococcal urethritis (NCNGU), 58 with infectious mononucleosis (IM), 91 with other systemic or non-genitourinary infections such as varicella; and 125-258 men with no

SUBMITTER: Langston ME 

PROVIDER: S-EPMC6690490 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature