Polymorphous adenocarcinoma of salivary glands.

ABSTRACT:

Objective

Polymorphous adenocarcinoma of salivary gland (PAC) is rare. Despite being described as a low risk histology, some patients develop regional and distant metastasis. More aggressive behavior has been attributed to a PAC subcategory called cribriform adenocarcinoma of minor salivary glands (CAMSG). We examined oncological outcomes of PAC.

Patients and methods

Fifty-seven patients with PAC were identified from an institutional database of 884 patients surgically treated for salivary gland malignancies from 1985 to 2015. Detailed histopathological analysis was performed. Survival outcomes were calculated using the Kaplan-Meier method. Factors predictive of recurrence were identified using the Cox proportional hazard method.

Results

Fifty-four (95%) had tumors of

SUBMITTER: Mimica X 

PROVIDER: S-EPMC6698324 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature