Association Between Weight Loss Before Deceased Donor Kidney Transplantation and Posttransplantation Outcomes.

ABSTRACT:

Rationale & objective

There is debate on whether weight loss, a hallmark of frailty, signals higher risk for adverse outcomes among recipients of deceased donor kidney transplantation (DDKT).

Study design

Retrospective cohort study.

Setting & participants

Using national Organ Procurement and Transplantation Network data, we included all DDKT recipients in the United States between December 4, 2004, and December 3, 2014, who were adults (aged ≥ 18 years) when listed for DDKT.

Exposures

Relative pre-DDKT weight change as a continuous predictor and categorized as <5% weight change from listing to DDKT, ≥5% to <10% weight loss, ≥10% weight loss, ≥5% to <10% weight gain, and ≥10% weight gain.

Outcomes

We examined 3 post-DDKT outcomes: (1) transplant hospitali

SUBMITTER: Harhay MN 

PROVIDER: S-EPMC6708783 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature