Fast media optimization for mixotrophic cultivation of Chlorella vulgaris.

ABSTRACT: Microalgae can accumulate large proportions of their dry cell weight as storage lipids when grown under appropriate nutrient limiting conditions. While a high ratio of carbon to nitrogen is often cited as the primary mode of triggering lipid accumulation in microalgae, fast optimization strategies to increase lipid production for mixotrophic cultivation have been difficult to developed due to the low cell densities of algal cultures, and consequently the limited amount of biomass available for compositional analysis. Response surface methodologies provide a power tool for assessing complex relationships such as the interaction between the carbon source and nitrogen source. A 15 run Box-Behnken design performed in shaker flasks was effective in studying the effect of carbon, nitrogen, and m

SUBMITTER: Ward VCA 

PROVIDER: S-EPMC6917816 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature