Herpes simplex virus and Cytomegalovirus reactivation among severe ARDS patients under veno-venous ECMO.

ABSTRACT:

Background

Herpesviridae reactivation among non-immunocompromised critically ill patients is associated with impaired prognosis, especially during acute respiratory distress syndrome (ARDS). However, little is known about herpes simplex virus (HSV) and Cytomegalovirus (CMV) reactivation occurring in patients with severe ARDS under veno-venous extracorporeal membrane oxygenation (ECMO). We tried to determine the frequency of Herpesviridae reactivation and its impact on patients' prognosis during ECMO for severe ARDS.

Results

During a 5-year period, 123 non-immunocompromised patients with a severe ARDS requiring a veno-venous ECMO were included. Sixty-seven patients (54%) experienced HSV and/or CMV reactivation during ECMO course (20 viral co-infection, 40 HSV alone, and 7 CMV

SUBMITTER: Hraiech S 

PROVIDER: S-EPMC6928167 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature