Dataset Information

Genotoxic and Carcinogenic Potential of Compounds Associated with Electronic Cigarettes: A Systematic Review.

ABSTRACT:

Background

Many studies, comparing the health associated risks of electronic cigarettes with conventional cigarettes focus mainly on the common chemical compounds found between them.

Aim

Review chemical compounds found exclusively in electronic cigarettes and describe their toxic effects, focusing on electronic-cigarette-only and dual electronic-cigarette and conventional cigarette users.

Data sources

Literature search was carried out using PubMed.

Study eligibility criteria

Articles related exclusively to conventional and electronic cigarettes' chemical composition. Articles which reported to be financed from tobacco or electronic cigarettes industries, not reporting source of funding, not related to the chemical composition of electronic and conventional cigarettes and not relevant to tobacco research were excluded.

Methods and results

Chemical compounds reported in the selected studies were tabulated using the Chemical Abstracts Service registry number for chemical substances information. A total of 50 chemical compounds were exclusively reported to be present in electronic cigarettes. Crucial health risks identified were: eye, skin, and respiratory tract irritation, with almost 50% of incidence, an increment of 10% in cytotoxic effects, when compared to compounds in common with conventional cigarettes and around 11% of compounds with unknown effects to human health.

Limitations

Articles reporting conflicts of interest.

Conclusions and implications of key findings

Despite being considered as less harmful for human health, compounds found in electronic cigarettes are still a matter of research and their effects on health are yet unknown. The use of these devices is not recommended for first time users and it is considered hazardous for dual users.

SUBMITTER: Armendariz-Castillo I

PROVIDER: S-EPMC6948324 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Genotoxic and Carcinogenic Potential of Compounds Associated with Electronic Cigarettes: A Systematic Review.

Armendáriz-Castillo Isaac I Guerrero Santiago S Vera-Guapi Antonella A Cevallos-Vilatuña Tiffany T García-Cárdenas Jennyfer M JM Guevara-Ramírez Patricia P López-Cortés Andrés A Pérez-Villa Andy A Yumiceba Verónica V Zambrano Ana K AK Leone Paola E PE Paz-Y-Miño César C

BioMed research international 20191219

<h4>Background</h4>Many studies, comparing the health associated risks of electronic cigarettes with conventional cigarettes focus mainly on the common chemical compounds found between them.<h4>Aim</h4>Review chemical compounds found exclusively in electronic cigarettes and describe their toxic effects, focusing on electronic-cigarette-only and dual electronic-cigarette and conventional cigarette users.<h4>Data sources</h4>Literature search was carried out using PubMed.<h4>Study eligibility crit ...[more]

PMID: 31950030

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Dataset Information

Genotoxic and Carcinogenic Potential of Compounds Associated with Electronic Cigarettes: A Systematic Review.

Background

Aim

Data sources

Study eligibility criteria

Methods and results

Limitations

Conclusions and implications of key findings

Publications

Genotoxic and Carcinogenic Potential of Compounds Associated with Electronic Cigarettes: A Systematic Review.

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