Ontology highlight
ABSTRACT:
SUBMITTER: McIntyre ABR
PROVIDER: S-EPMC7170965 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Scientific reports 20200420 1
Many cellular mRNAs contain the modified base m<sup>6</sup>A, and recent studies have suggested that various stimuli can lead to changes in m<sup>6</sup>A. The most common method to map m<sup>6</sup>A and to predict changes in m<sup>6</sup>A between conditions is methylated RNA immunoprecipitation sequencing (MeRIP-seq), through which methylated regions are detected as peaks in transcript coverage from immunoprecipitated RNA relative to input RNA. Here, we generated replicate controls and reanal ...[more]