Gestational Age, Perinatal Characteristics, and Autism Spectrum Disorder: A Birth Cohort Study.

ABSTRACT:

Objective

To determine how gestational age relates to research-identified autism spectrum disorder (ASD-R) in the context of perinatal risk factors.

Study design

This is a population-based cohort study using the 1994-2000 Olmsted County Birth Cohort. Children included were born and remained in Olmsted County after age 3 years. ASD-R status was determined from signs and symptoms abstracted from medical and educational records. Cox proportional hazards models were fit to identify associations between perinatal characteristics and ASD-R.

Results

The incidence of preterm birth (<37 weeks' gestation) was 8.6% among 7876 children. The cumulative incidence of ASD-R was 3.8% (95% CI 3.3-4.2) at 21 years of age. Compared with children born at full term, the risk of ASD-R appea

SUBMITTER: Brumbaugh JE 

PROVIDER: S-EPMC7186146 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature