The Cost-Effectiveness of Cognitive Behavioral Therapy Versus Second-Generation Antidepressants for Initial Treatment of Major Depressive Disorder in the United States: A Decision Analytic Model.

ABSTRACT: Background: Most guidelines for major depressive disorder recommend initial treatment with either a second-generation antidepressant (SGA) or cognitive behavioral therapy (CBT). Although most trials suggest that these treatments have similar efficacy, their health economic implications are uncertain.

Objective: To quantify the cost-effectiveness of CBT versus SGA for initial treatment of depression.

Design: Decision analytic model.

Data sources: Relative effectiveness data from a meta-analysis of randomized controlled trials; additional clinical and economic data from other publications.

Target population: Adults with newly diagnosed major depressive disorder in the United States.

Time horizon: 1 to 5 years.

SUBMITTER: Ross EL 

PROVIDER: S-EPMC7188559 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature