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Sex difference in the incidence of microvascular complications in patients with type 2 diabetes mellitus: a prospective cohort study.


ABSTRACT:

Aims

Type 2 diabetes mellitus is a major cause of death and disability due to its long-term macro- and microvascular diseases. Although women with type 2 diabetes have more macrovascular diseases, it is unclear whether there are sex differences in the occurrence of microvascular disease. The aim of our study was to investigate sex differences in the incidence of microvascular complications in type 2 diabetes.

Methods

Analyses were performed in the DiaGene study, a prospective cohort study for complications of type 2 diabetes, collected in the city of Eindhoven, the Netherlands (n = 1886, mean follow-up time = 6.93 years). Cox proportional hazard models adjusted for risk factors for complications (age, smoking, hypertension, dyslipidemia, HbA1c and duration of type 2 diabetes

SUBMITTER: Singh SS 

PROVIDER: S-EPMC7220974 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature