Characteristics of COVID-19 Clinical Trials in China Based on the Registration Data on ChiCTR and ClinicalTrials.gov.

ABSTRACT:

Objective

This study aimed to evaluate the fundamental characteristics of coronavirus disease (COVID-19) clinical trials registered in China.

Methods

COVID-19 clinical trials registered in China were analyzed from databases on ChiCTR and ClinicalTrials.gov. The study designs, samples, primary end points, and intervention measures were evaluated.

Results

In total, 262 intervention clinical trials were retrieved on March 10, 2020. Overall, 181 (69.1%) trials involved two groups, 200 (76.3%) trials were randomized parallel trials, 24 (9.2%) trials were double blind, and 60.3% of trials included ≤100 participants. Sixty (22.9%) trials considered symptom improvement as the primary endpoint and 43 (16.4%) trials considered the rate or time at which the subjects became virus

SUBMITTER: Huang J 

PROVIDER: S-EPMC7266821 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature