Automated cot-side tracking of functional brain age in preterm infants.

ABSTRACT:

Objective

A major challenge in the care of preterm infants is the early identification of compromised neurological development. While several measures are routinely used to track anatomical growth, there is a striking lack of reliable and objective tools for tracking maturation of early brain function; a cornerstone of lifelong neurological health. We present a cot-side method for measuring the functional maturity of the newborn brain based on routinely available neurological monitoring with electroencephalography (EEG).

Methods

We used a dataset of 177 EEG recordings from 65 preterm infants to train a multivariable prediction of functional brain age (FBA) from EEG. The FBA was validated on an independent set of 99 EEG recordings from 42 preterm infants. The difference betwe

SUBMITTER: Stevenson NJ 

PROVIDER: S-EPMC7318094 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature