Impact of lower body mass index on risk of all-cause mortality and infection-related death in Japanese chronic kidney disease patients.

ABSTRACT:

Background

Several studies have reported that lower body mass index (BMI) is associated with high mortality in patients with chronic kidney disease (CKD). Rate of infection-related death in CKD patients is increasing. However, the relationship between BMI and infection-related death is unclear.

Methods

Overall, 2648 CKD outpatients (estimated glomerular filtration rate < 60 mL/min and/or presenting with proteinuria) under the care of nephrologists were prospectively followed for 5 years. Patients were stratified by quartile of BMI levels. Data on all-cause mortality before progression to end-stage kidney disease (ESKD) and the cause of death were collected.

Results

The median follow-up time was 3.9 years (interquartile range, 1.7-5.0); 114 patients died and 308 starte

SUBMITTER: Yamamoto T 

PROVIDER: S-EPMC7325015 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature