Outcomes After Multidisciplinary Management of Primary Mediastinal Germ Cell Tumors.

ABSTRACT:

Objective

We examined management strategies, overall survival (OS), and progression-free survival (PFS) among patients with PMNSGCTs undergoing resection and multidisciplinary management at a high-volume institution.

Summary of background data

Outcomes after resection of PMNSGCTs are not well-characterized, with limited data on factors associated with survival.

Methods

We reviewed patients with PMNSGCT who underwent resection between 1980 and 2019. Median follow-up was 3.4 years. Preoperative therapy (including use of bleomycin), surgical management, recurrence, and survival were examined. Factors associated with survival were analyzed using Cox regression.

Results

In total, 113 patients were included [median age, 28 years (range, 16-65)]. Preoperative serum tu

SUBMITTER: Caso R 

PROVIDER: S-EPMC7371518 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature