Systematic evaluation of velocity-selective arterial spin labeling settings for placental perfusion measurement.

ABSTRACT:

Purpose

Placental function is key for successful human pregnancies. Perfusion may be a sensitive marker for the in vivo assessment of placental function. Arterial spin labeling (ASL) MRI enables noninvasive measurement of tissue perfusion and it was recently suggested that ASL with velocity-selective (VS) labeling could be advantageous in the placenta. We systematically evaluated essential VS-ASL sequence parameters to determine optimal settings for efficient placental perfusion measurements.

Methods

Eleven pregnant women were scanned at 3T using VS-ASL with 2D multislice echo planar imaging (EPI)-readout. One reference VS-ASL scan was acquired in all subjects; within subgroups the following parameters were systematically varied: cutoff velocity, velocity encoding direction,

SUBMITTER: Harteveld AA 

PROVIDER: S-EPMC7384055 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature