Gene expression analysis of primary gingival cancer by whole exome sequencing in thirteen Chinese patients.
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ABSTRACT:
SUBMITTER: Liu GM
PROVIDER: S-EPMC7414513 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Gene expression analysis of primary gingival cancer by whole exome sequencing in thirteen Chinese patients.
Liu Guo-Min GM Lu Tian-Cheng TC Liu Yun Y Luo Yun-Gang YG
International journal of clinical and experimental pathology 20200701 7
<h4>Objectives</h4>Early diagnosis of and markers for gingival oral squamous cell carcinoma (OSCC) is important for effective treatment.<h4>Methods</h4>The current study performed a whole exome sequencing of gingival OSCC tissues in thirteen Chinese patients to explore exonic mutants.<h4>Results</h4>Eighty-five genes emerged as mutants in patients with primary gingival OSCC. CCL4L1 presented a G>A transversion at chr17 17q12, position 36212480, exon 3. KDM5B presented a T>TA insertion at chr1 1q ...[more]
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