Effective connectivity during autobiographical memory search.

ABSTRACT:

Introduction

We used dynamic causal modeling (DCM) to examine effective connectivity during cued autobiographical memory (AM) search in a left-hemispheric network consisting of six major regions within the large network of brain regions recruited during memory retrieval processes.

Methods

Functional MRI data were acquired while participants were shown verbal cues describing common life events and requested to search for a personal memory associated with the cue. We examined directed couplings between the ventromedial (vmPFC), dorsomedial (dmPFC), and dorsolateral prefrontal cortices (dlPFC), hippocampus, angular gyrus, and the posterior midline cortex (RSC/PCC/Prec).

Results

During AM search, the vmPFC, dlPFC, and RSC/PCC/Prec acted as primary drivers of activity in t

SUBMITTER: Nawa NE 

PROVIDER: S-EPMC7428471 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature