The association between chronic kidney disease and tuberculosis; a comparative cohort study in England.

ABSTRACT:

Background

People with end-stage kidney disease have an increased risk of active tuberculosis (TB). Previous systematic reviews have demonstrated that patients with chronic kidney disease (CKD) have increased risk of severe community-acquired infections. We investigated the association between CKD (prior to renal replacement therapy) and incidence of TB in UK General Practice.

Methods

Using the UK Clinical Practice Research Datalink, 242,349 patients with CKD (stages 3-5) (estimated glomerular filtration rate < 60 mL/min/1.73 m² for ≥3 months) between April 2004 and March 2014 were identified and individually matched (by age, gender, general practice and calendar time) to a control from the general population without known CKD. The association between CKD (overall

SUBMITTER: Ruzangi J 

PROVIDER: S-EPMC7528250 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature