Serum levels of allopregnanolone, progesterone and testosterone in menstrually-related and postmenopausal migraine: A cross-sectional study.

ABSTRACT:

Background

Reduced blood or cerebrospinal fluid levels of allopregnanolone are involved in menstrual cycle-linked CNS disorders, such as catamenial epilepsy. This condition, like menstrually-related migraine, is characterized by severe, treatment-resistant attacks. We explored whether there were differences in allopregnanolone, progesterone and testosterone serum levels between women with menstrually-related migraine (MM, n = 30) or postmenopausal migraine without aura who had suffered from menstrually-related migraine during their fertile age (PM, n = 30) and non-headache control women in fertile age (FAC, n = 30) or post-menopause (PC, n = 30).

Methods

Participants were women with migraine afferent to a headache centre; controls were female patients' acquaintances. Serum s

SUBMITTER: Rustichelli C 

PROVIDER: S-EPMC7575305 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature