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Activation of pentafluoropropane isomers at a nanoscopic aluminum chlorofluoride: hydrodefluorination versus dehydrofluorination.

ABSTRACT: The hydrofluorocarbon 245 isomers, 1,1,1,3,3-pentafluoropropane, 1,1,1,2,2- pentafluoropropane, and 1,1,1,2,3-pentafluoropropane (HFC-245fa, HFC-245cb, and HFC-245eb) were activated through C-F bond activations using aluminium chlorofluoride (ACF) as a catalyst. The addition of the hydrogen source Et₃SiH is necessary for the activation of the secondary and tertiary C-F bonds. Multiple C-F bond activations such as hydrodefluorinations and dehydrofluorinations were observed, followed by hydroarylation and Friedel-Crafts-type reactions under mild conditions.

SUBMITTER: Kervarec MC

PROVIDER: S-EPMC7590627 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Activation of pentafluoropropane isomers at a nanoscopic aluminum chlorofluoride: hydrodefluorination versus dehydrofluorination.

Kervarec Maëva-Charlotte MC Braun Thomas T Ahrens Mike M Kemnitz Erhard E

Beilstein journal of organic chemistry 20201023

The hydrofluorocarbon 245 isomers, 1,1,1,3,3-pentafluoropropane, 1,1,1,2,2- pentafluoropropane, and 1,1,1,2,3-pentafluoropropane (HFC-245fa, HFC-245cb, and HFC-245eb) were activated through C-F bond activations using aluminium chlorofluoride (ACF) as a catalyst. The addition of the hydrogen source Et<sub>3</sub>SiH is necessary for the activation of the secondary and tertiary C-F bonds. Multiple C-F bond activations such as hydrodefluorinations and dehydrofluorinations were observed, followed by ...[more]

PMID: 33133293

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