Magnetic resonance imaging measurement of placental perfusion and oxygen saturation in early-onset fetal growth restriction.

ABSTRACT:

Objective

We hypothesised that a multi-compartment magnetic resonance imaging (MRI) technique that is sensitive to fetal blood oxygenation would identify changes in placental blood volume and fetal blood oxygenation in pregnancies complicated by early-onset fetal growth restriction (FGR).

Design

Case-control study.

Setting

London, UK.

Population

Women with uncomplicated pregnancies (estimated fetal weight [EFW] >10th centile for gestational age [GA] and normal maternal and fetal Doppler ultrasound, n = 12) or early-onset FGR (EFW <3rd centile with or without abnormal Doppler ultrasound <32 weeks GA, n = 12) were studied.

Methods

All women underwent MRI examination. Using a multi-compartment MRI technique, we quantified fetal and maternal blood volume and

SUBMITTER: Aughwane R 

PROVIDER: S-EPMC7613436 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature