Long-Term Exposure to Fine Particulate Matter and Incidence of Esophageal Cancer: A Prospective Study of 0.5 Million Chinese Adults.

ABSTRACT:

Background & aims

Evidence is sparse and inconclusive on the association between long-term fine (≤2.5 μm) particulate matter (PM_2.5) exposure and esophageal cancer. We aimed to assess the association of PM_2.5 with esophageal cancer risk and compared the esophageal cancer risk attributable to PM_2.5 exposure and other established risk factors.

Methods

This study included 510,125 participants without esophageal cancer at baseline from China Kadoorie Biobank. A high-resolution (1 × 1 km) satellite-based model was used to estimate PM_2.5 exposure during the study period. Hazard ratios (HR) and 95% CIs of PM_2.5 with esophageal cancer incidence were estimated using Cox proportional hazard model. Population attributable fractions

SUBMITTER: Sun D 

PROVIDER: S-EPMC7615725 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature