Peptide YY_3-36 concentration in acute- and long-term recovered anorexia nervosa.

ABSTRACT:

Purpose

The gut-brain axis could be a possible key factor in the pathophysiology of anorexia nervosa. The neuropeptide peptide YY_3-36, secreted by endocrine L cells of the gastrointestinal tract, is a known regulator of appetite and food intake. The objective of this study was to investigate peptide YY_3-36 plasma concentrations at different stages of anorexia nervosa in a combined cross-sectional and longitudinal design to differentiate between effects of acute undernutrition and more enduring characteristics.

Methods

We measured fasting plasma peptide YY_3-36 concentrations in young patients with acute anorexia nervosa (n = 47) and long-term recovered patients (n = 35) cross-sectionally in comparison to healthy control participants (n = 58),

SUBMITTER: Tam FI 

PROVIDER: S-EPMC7669786 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature